To date little is known about the health status of the 7.3 million Americans who signed up for health insurance through either federal- or state-run exchanges created by the Affordable Care Act (ACA). One effective way to gain information is to examine their use of prescription drugs. A new study, being released by Health Affairs as a Web First, compared prescription data from January to September of 2014 of more than one million Marketplace enrollees. The study reviewed the characteristics and medication use of early enrollees (October 1, 2013 through February 28, 2014) and those enrolling later (between March 1 and May 31, 2014), and compared those findings with a sample of some one million Americans enrolled in employer-sponsored health coverage. There were three key findings, which have implications for understanding the