MEDI4736 combined with tremelimumab results in acceptable toxicity in NSCLC patients

Posted on by admin

Advanced non-small cell lung cancer patients have few effective treatment options and low 5-year survival rates. The checkpoint inhibitors MEDI4736 and tremelimumab have both demonstrated acceptable safety and potential efficacy when used as single-agents in several different types of cancer.


SOURCE: Top Health News — ScienceDaily – Read entire story here.

Related posts:

  1. Portable finger-probe device can successfully measure liver function in potential organ donors A portable, finger-probe device successfully measured liver function in brain dead adult organ donors, a finding that could change the way organs are assessed and save thousands of dollars per transplant, a study has found. ...
  2. Chronic myelomonocytic leukemia: JAK2 inhibitor ruxolitinib has promising efficacy Scientists are reporting on the first phase 1 study of the JAK2 inhibitor ruxolitinib in CMML patients. ...
  3. Phase 2 trial identifies genetic dysfunction that makes many types of cancer vulnerable to an immunotherapy A team of researchers has identified a genetic malfunction that predicts the effectiveness of response to a groundbreaking immunotherapy. The results of their Phase 2 clinical trial reveal that, regardless of its tissue of origin, tumors whose cells are deficient in repairing mismatched DNA sequences--and so preventing mutations--are far more susceptible to the checkpoint inhibitor pembrolizumab than those that retain this ability. ...
  4. ONT-380 has stage IV HER2+ breast cancer patient ‘worrying about normal stuff again’ Promising clinical trial results show activity of the investigational anti-cancer agent ONT-380 against HER2+ breast cancer, in one case specifically against brain metastases and in another case in overall survival of heavily pretreated HER2+ breast cancer patients. ...
  5. Officers fatally shoot knife-wielding man in Lyndhurst library, police say A Lyndhurst man wanted for failing to show up for a jail work-release program was fatally shot by police early Friday afternoon inside the Lyndhurst library after he assaulted officers with a knife, authorities said. Bergen County Prosecutor John L. Molinelli identified the suspect killed in the police-involving shooting as Kevin Allen of Lyndhurst. ...

Related Posts