Of the many methods of slowing aging discovered to date most have only a small effect in short-lived species such as mice, around a 10{c754d8f4a6af077a182a96e5a5e47e38ce50ff83c235579d09299c097124e52d} increase in healthy or maximum life span. Based on what we know of methods where we do have data for comparison, such as calorie restriction, these methodologies are expected to have even smaller effects in longer-lived species such as ourselves. Worth spending time on? Probably not. We need to chase after new and better biotechnology that can provide comprehensive repair of the damage that causes aging, not slight optimizations to our internal engines so that they wear out just a little bit more slowly. Interestingly, many methods of modestly slowing aging in mammals such as mice have strongly gender-specific