Minimal residual disease alone not predictive in T-cell leukemia

Researchers found that the presence of a few remaining leukemia cells, called minimal residual disease (MRD), at the end of induction chemotherapy was not predictive of risk or outcome in children with T-cell acute lymphoblastic leukemia (ALL). This opens the possibility for patients with T-cell ALL who have MRD to achieve complete remission without undergoing intensified cancer treatments and their associated toxicities.

Educating the immune system to prevent allergies

With the arrival of spring, millions of people have begun their annual ritual of sneezing and wheezing due to seasonal allergies. A research team is bringing them hope with a potential vaccine that nudges the immune response away from developing allergies. The findings have major clinical implications since allergies and asthma often start in childhood and for which there is presently no cure.

Children’s views should shape how research is conducted, says ethics body

A new report calls for a change in culture across all areas of children’s health research, so that children’s and young people’s views and opinions can help to shape how research is prioritized, designed and reviewed. Unless ethical concerns about asking children to take part in research are addressed, our understanding of childhood disorders and ability to provide evidence based care will remain limited.

Are some children born naughty?

A new Channel 4 series about children with serious behavioural issues asks if nature can take the blame – rather than the long-suffering parents