Ossur to announce clinical trials for implanted myoelectric sensors for brain-controlled prosthetics

Ossur, an Icelandic based prosthetics development company is set to announce the beginning of clinical trials for its Proprio foot, a new kind of brain controlled prosthetic ankle and foot. Instead of trying to connect the device to nerves, the robotic limb uses sensors to detect nerve signals in muscles near the point where the limb was removed. The limb then analyses those signals and converts them to movement in real time, which is reportedly very close to that of natural limbs.

Obesity and weight loss change splicing pattern of obesity and type 2 diabetes genes

Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to changes in the splicing pattern of metabolically relevant genes such as TCF7L2 and INSR, resulting in impaired insulin action. However, weight loss, induced by either obesity surgery or a very low-calorie diet, reverses these changes. The findings, presented by Dorota Kaminska, MSc, in her doctoral dissertation, increase our understanding of splicing dysregulations in obesity and can result in a new, more targeted treatment and more accurate diagnostics of metabolic disorders.

Targeted drug delivery could transform therapies

A world expert in biomedical engineering will today argue that medical science has been focusing on the wrong problem for 30 years. Instead of inventing new drugs, making better use of the drugs we already have available by targeting them to the affected part of the body could hold the answer to tackling many of today’s life threatening diseases.

How to Manage High Medical Bills

Many Americans lack the savings necessary to pay for sizable health care costs. Here’s a look at some helpful strategies to handle these payments.

‘Green chemistry’ to quantify the components of cosmetics

There are 10,000 components that can be used to make cosmetics. These components have to be monitored to guarantee consumer safety. Scientists have now developed three ‘green’ analytical methods to simultaneously analyze various components used in cosmetics. In these methods very little solvent is used and very little residue is produced in comparison with other analytical techniques.

Hep C irony renews questions of public confidence

In a nice touch of media irony, on the very day that Gilead Sciences, Inc. purchased a full page ad in the New York Times (web version here) talking about “new resources” available to fight Hepatitis C, a story by Andrew Pollack started with this lede:Activists in several countries are seeking to void patents on the blockbuster hepatitis C drug Sovaldi, saying that the price being sought by the manufacturer, Gilead Sciences, was prohibitive.The Initiative for Medicines, Access and Knowledge, a legal group in New York, is expected to announce Wednesday that it has filed challenges in Argentina, Brazil, China, Russia and Ukraine. In all those countries except China, the organization is being joined by local patient advocacy groups.The actions are a sign that

New hospital ratings evaluate delivery of “typical care”

The Internet has made it easier to become an educated consumer. At the touch of a button, you can find reviews of thousands of products and services — even health services — from consumer groups and fellow customers. It’s no surprise that many people count on these reviews and rankings before visiting a hospital. For the past 25 years, US News and World Report has been listing the “best hospitals” in the United States. In a Viewpoint article in this week’s JAMA, the magazine’s top health analysts describe how they are expanding and changing the way they rate hospitals. Common procedures, conditions will be included Since 1990, US News has analyzed information from about 2,000 large hospitals in the United States and ranked the top 50 in